2nd July, 2009 - Posted by admin - No Comments
That was the lead headline screaming from my intelligence database this morning, from several sources. On checking the Pfizer website, to verify the information, I found the following in a terse press release : “Pfizer Inc announced today the discontinuation of the SUN 1122 Phase 3 trial that evaluated Sutent ® (sunitinib malate) plus FOLFIRI (irinotecan plus infusional 5-fluorouracil and leucovorin) versus FOLFIRI alone for the first-line treatment of metastatic colorectal cancer (CRC). The independent Data Monitoring Committee (DMC) found that the addition of sunitinib to the chemotherapy regimen FOLFIRI would be unable to demonstrate a statistically significant improvement in the primary endpoint of progression-free survival (PFS) compared to FOLFIRI alone, in this study. No new safety issues were identified.” It would therefore seem that small molecule TKI’s are not the way to go with this disease given that Novartis’ vatalanib also failed in phase III trials of a similar nature. Genentech’s Avastin acts differently, targeting the outside of the receptor as a monoclonal antibody. Read More
1st July, 2009 - Posted by admin - No Comments
In many ways, things are probably going a lot faster than many of us realise in the digital age as blogging and RSS aggregation gives way to lifestreaming and real time information… Read More
1st July, 2009 - Posted by admin - No Comments
One powerful action you can take to both lower your carbon footprint and to save some cash is to start commuting by bicycle. You can ride to work, ride to the grocery store, and you can haul your kids (or dog) around town, and you’ll probably boost your health at the same Post from: Green Living Ideas Bicycle Commuting Survival Guide Related Posts Bike to Work and Get Paid for It Cycling, The Ultimate in Green Energy Transport Climate Cycle: Chicago Rides Toward Solar Powered Schools Electric Bicycles: Green Your Bike Commute Green Gifting Guide: Green Gifts for Grown-Ups Read More
1st July, 2009 - Posted by admin - No Comments
The Ayurvedic treatment is always pe.. Read More
1st July, 2009 - Posted by admin - No Comments
Small breast size is a matter of concern and pride for a number of women. Women with smaller breasts tend to suffer from inferiority complex and low self confidence and they seem to be less attractive to men who always want a woman with a bigger breast size. Read More
1st July, 2009 - Posted by admin - No Comments
The drugs of grass are but a sfaccettatura of the practical alternatives in the medical field, however Interesting, many of the common prescription and l’ surplus against drugs used today obtains their roots from the natural substances. Some examples include l’ opium, that it comes from seeds of the plant of the poppy and the aspirin that is a by-product of the corteccia of the trees of the salice. Read More
1st July, 2009 - Posted by admin - No Comments
Alien Alternative medicines come in many forms and Ayurvedic is one of them. Many people have not heard of this healing medium as it only came to the fore in 1980 although the practice of Ayurvedic healing is said to be over 5000 years old.Ayurvedic means life and knowledge Read More
1st July, 2009 - Posted by admin - No Comments
Where in the eyes of the law cars have taken priority over people, new laws requiring disabled pedestrians to wear traff Read More
1st July, 2009 - Posted by admin - No Comments
Japanese scientists have achieved a breakthrough in advancing towards the next generation of genetically modified rice, Read More
1st July, 2009 - Posted by admin - No Comments
Feeding mice on a diet high in sunflower oil improves their running abilities by about 6.3 percent, which is equivalent Read More
