Archive for the 'Medicines' Category

 Ayurveda Medicines, Ayurvedic Herbs and Ayurvedic Treatments by …

Ayurveda Medicines, Ayurvedic Herbs and Ayurvedic Treatments – a free article by Dev SriRelated posts: Ayurveda Medicines, Ayurvedic Herbs and Ayurvedic Treatments; Ayurveda and Ayurvedic Medicines; Ayurveda, Ayurvedic Medicines and …



 Angiogenesis, angiopoeitin and Glioblastoma Multiforme (GBM)

Read and writing about malignant brain cancers, gliomas or glioblastoma multiforme (GBM) always makes me sad as life span from diagnosis is often only a year. Over the last decade we have seen many advances in surgery, radiation, chemotherapy and targeted therapies in many cancers, yet this one remains largely immune to significant progress. Background Angiogenesis inhibitors targeting the VEGF signaling pathway have been shown to be effective both in preclinical cancer models and in clinical trials.



 Evaluation of rationality of promotional drug literature using …

orthopedic prosthesis and ayurvedic medicines, drug monographs, reminder advertisements (reminder advertisements do not present any therapeutic information and have different criteria for evaluation), drugs name list, and literature …. Important information regarding adverse drug reactions , contraindications, or drug interactions was usually missing. Reference citations were given to earn credibility, but it was difficult to trust them because of ambiguous presentation, …



 MET and KRAS amplification mediate resistance to MET inhibitors

Here's an interesting paper that was just published in Cancer Research that describes some factors driving acquired resistance to MET inhibition with small molecules. MET inhibitors have gained a lot of attention recently (see Comoglio et al's review in the references for a good overview) and we have covered this topic a few times on this blog both in terms of the biology and also on promising inhibitors such as ArQule/DaiichiSankyo's ARQ-197 , which is the leading compound in this field. Acquired resistance is a common and limiting problem for chronic therapy with many tyrosine kinase inhibitors (TKI), not just MET inhibitors



 Aerobics for the Brain

As people age, brain function slowly declines. Aside from improving physical fitness and overall health, exercise may also help improve brain function in older adults, researchers report . In a study published in the journal Frontiers in Aging Neuroscience , researchers evaluated brain function by performing magnetic resonance imaging (MRI) scans on 70 sedentary (but otherwise healthy) adults who were 60-80 years old



 Resveratrol for Heart Health

New research suggests that supplementation with resveratrol, a polyphenol found in red wine, grapes and other plants, may help improve circulatory function. Resveratrol is commonly believed to help prevent heart disease. Interest in resveratrol has been increasing since the 1990s, when it was discovered that coronary heart disease was less common in France compared to other developed nations



 Sisyphus, oncology R&D and Pharma

Loved this cartoon from Hugh Macleod at Gaping Void that just arrived in my mail box: Source: Gaping Void In many ways, this is what drug development can look like on a day to day basis. Scientists repeating experiments, project teams holding endless meetings etc, that sometimes it's hard to see which in a portfolio of agents might actually make it through to market and which will fail along the journey



 Cerebral Palsy – Ayurvedic Herbal Treatment

Cerebral palsy refers to a group of neurological disorders that appear in infancy or childhood and permanently affect body movement and muscle co-ordination. Symptoms include a lack of muscle co-ordination when performing voluntary movements (ataxia); stiff or tight muscles and exaggerated reflexes (spasticity); walking with one foot or leg dragging; walking on the toes, a crouched gait, or a ’scissored ‘ gait; and muscle tone that is either too stiff or too floppy



 Insight on Herbals Eludes Doctors, Patients Alike

(HealthDay News) — Medical personnel tend to think that people in general — themselves included — are poorly informed about herbal medicines and that their patients’ faith in the power of such remedies is misplaced, according to a new survey. The survey was conducted online among 164 subscribers to the journal Drug and Therapeutics Bulletin, which published the results online April 8



 The Land of Giants Wins Award, But No Build Date

Here’s a great solution to the NIMBYism that building new transmission dredges up, commissioned by Landsnet, a public company that owns and runs the electrical transmission system in Iceland. Elegant transmission pylons that look like Art. “Like the statues of Easter Island, it is envisioned that these one hundred and fifty foot [ The Land of Giants Wins Award, But No Build Date from Green Living Ideas ]